The Clinical Efficacy of Azathioprine in Korean Patients with Atopic Dermatitis.

نویسندگان

  • Hemin Lee
  • Jung U Shin
  • Kwang Hoon Lee
چکیده

774 Ann Dermatol Received September 15, 2014, Revised February 12, 2015, Accepted for publication February 18, 2015 Corresponding author: Kwang Hoon Lee, Department of Dermatology and Cutaneous Biology Research Institute, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea. Tel: 82-2-2228-2084, Fax: 82-2-393-9157, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fig. 1. Change in the eczema area and severity index (EASI) score before and after azathioprine treatment (mean treatment duration, 22.20±19.84 weeks). There was a 42% reduction in the EASI score from the baseline (p<0.017). *Statistically significant difference compared with the baseline. incidence and complications of herpes zoster: towards a global perspective. BMJ Open 2014;4:e004833. 7. Chen N, Li Q, Yang J, Zhou M, Zhou D, He L. Antiviral treatment for preventing postherpetic neuralgia. Cochrane Database Syst Rev 2014;2:CD006866. 8. Winnie AP, Hartwell PW. Relationship between time of treatment of acute herpes zoster with sympathetic blockade and prevention of post-herpetic neuralgia: clinical support for a new theory of the mechanism by which sympathetic blockade provides therapeutic benefit. Reg Anesth 1993;18: 277-282.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The efficacy of phototherapy in treatment of resistant Atopic dermatitis

Background: Due to the chronic nature of atopic dermatitis and dependence of most patients to steroids, finding a suitable alternative treatment is important. Objectives: To determine the efficacy of phototherapy in treatment of atopic dermatitis, also to evaluate possible influencing factors in response of patients to psoralen+UVA (PUVA) therapy. Patients and Methods: 13 patients with resistan...

متن کامل

Cutaneous Leishmaniasis in Atopic Dermatitis Patients in Comparison with the Control Group in Kerman

Background: Atopic dermatitis is the most common chronic inflammatory dermatitis, due to immunological disorders. Patients with atopic dermatitis are prone to infectious diseases including bacterial infections. On the other hand, atopy may be protective against helminthes parasites. The objective of this study was to compare the frequency and clinical presentations of cutaneous leishmaniasis in...

متن کامل

Evaluation of clinical efficacy and tolerability of azathioprine in adult Chinese atopic dermatitis patients in Hong Kong with pre-treatment thiopurine methyltransferase assessment

Background: Azathioprine (AZA) has been proposed as an off-label option in treating moderateto-severe atopic dermatitis. Pre-treatment thiopurine methyltransferase (TPMT) assessment is commonly used in western countries, but TPMT test is not commonly available locally. Objective: We sought to evaluate the efficacy and tolerability of AZA in adult Chinese atopic dermatitis patients with pre-trea...

متن کامل

Association of LL-37 and IL-31 serum levels with SCORing Atopic Dermatitis (SCORAD) score in atopic dermatitis patients

Background: Atopic dermatitis is a chronic, recurrent inflammation of the skin, accompanied by severe pruritus. Immune system dysregulation and skin barrier defects are associated with the abnormalities in atopic dermatitis. Myriad pieces of evidence have pointed to the major roles of LL-37 and interleukin-31 (IL31)in atopic dermatitis. The studies on atopic dermatitis are still limited i...

متن کامل

Correlation of total serum IgE and density of house dust mites with severity of Atopic Dermatitis

Background and aim: Atopic dermatitis (AD) is a chronic relapsing skin disease that commonly begins during infancy and early childhood. Research studies refers to a relationship between exacerbation of atopic dermatitis and exposure to house dust mite (HDM), but the role of HDM in the pathogenesis of AD is controversial. The objecitve of this study was to assess the correlation of density...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Annals of dermatology

دوره 27 6  شماره 

صفحات  -

تاریخ انتشار 2015